The successful candidate will play a role in BeiGene’s biologics area focusing on stable cell pool/line development, cell line engineering, recombinant protein/antibody production and production platform development.
The candidate will join a team of internal & external biologics working across multiple projects.
Responsibilities:
- Design and conducting recombinant protein expression.
- Design and develop stable cell pool/line for recombinant protein production.
- Upstream process development for recombinant protein production platform and specific projects supported.
- Cell line engineering with CRISPR/overexpression/RNA interference technology.
- Demonstrated laboratory skills in recombinant protein/Ab expression, cell line development and cell line engineering.
- Good skills in mammalian expression system (CHO/HEK) are highly preferred.
- Other work assigned by line manager.
Qualiligications Required:
- MSc in molecular biology, biochemistry, cell biology, protein engineering or related discipline. Bachelor’s degree with minimum 2 years of work experiences.
- Expertise in cell cryopreservation, thaw, passaging, routine culture, cell cloning, and cell banking.
- Experience with mammalian cell transfection, genome editing, and characterization.
- Skill with WAVE system and bioreactor is a plus but not required.
- Skill with automated workstation is a plus but not required.
- Strong problem-solving skill and able to work independently.
- Candidate who demonstrates accountability, an outcome-focused mindset, a proactive approach, and a high degree of self-motivation.
- The ability to effectively communicate and collaborate with diverse teams.
- Good oral and written communication skills in Chinese; similar skill in English is a plus but not required.