Job Description:

- Scientifically lead a discovery research team developing innovative ways to manufacture cell product for clinical trial.

- Subject matter expert in CAR T cell process development and manufacturing.

- Execute research timelines to meet program and corporate objectives.

- Design, execute, and interpret process development study data to understand the mechanism-of-action and play an active role in subsequent scientific discussions to drive decisions.

- Write and review protocols, SOPs, technical reports, regulatory documents, and memos to summarize experiments and investigations.

- Partner with internal cross-functional team members to facilitate technical assessment, technical transfer, and IND filing.

- Closely mentor scientists to further develop talent within the group.

- Other duties will be assigned, as necessary.

Minimum Requirements/Qualifications:

- Ph.D. in Cell Biology, Immunology, Genetic Engineering, or related discipline.

- Minimum of 6+ years relevant pharmaceutical industry/academic experience post-graduation.

- Extensive hands-on experience with CRSIPR-genome engineering in multiple cell types.

- Independently design constructs and sgRNA for KO/KI through non-viral gene transfer technologies (EP, LNP) or viral transfer technologies (LVV, RVV, VLP).

- Profound skills in analytical methods including but not limited to flow cytometry, real-time PCR, off-target evaluation, NGS, dd PCR.

- Much experience in CAR-T, CAR-γδT, or CAR-NK cell immunotherapies, including cell culture, immune cell activation, expansion, viral transduction or /and non-viral gene transfer, in vitro & in vivo characterization.

- Team management experience is preferred.

- Excellent communication skills both in English and Chinese, detail-oriented organization skills, and team collaboration skills.

- Strong ability to edit data, report data, present findings to management is required.

- Ability to manage priorities and make decisions in a fast-paced environment to make sure deliverables are achieved in a timely fashion.

- A strong track record of scientific accomplishments, including first-author publications, patent applications, and/or presentations at major national meetings, is required.

- Occasional domestic or international travel required.