岗位简介

Job Description:

您将从事小分子新药的分析及分离工作；以通过分析仪器设备进行检测、从事分析方法开发、验证和分离纯化等工作为主；同时参与小分子药物的创新纯平台的搭建和优化、杂质分析和鉴定等工作；有机会接触到现有的先进的技术平台，引领药物发现新趋势；有机会和跨国药企药化专家面对面交流学习。

You will be engaged in the analysis and separation of small-molecule drugs, primarily focusing on testing by using analytical instruments, method development, validation, separation and purification. Simultaneously participate in the construction and optimization of innovative pure platforms for small molecule drugs, as well as impurity analysis and identification work. This role provides an opportunity to work with advanced technology platforms and lead the pharmaceutical discovery trends. You will also have the chance to engage in face-to-face exchanges with pharmaceutical experts from multinational companies.

工作职责

Job Responsibilities:

运用各种分离技术如Prep-HPLC为Medicinal Chemistry，Synthetic Chemistry，Library 提供的混合物进行纯化；

运用HPLC或SFC等方法提供专业快速的手性分析和手性分离服务；

运用各种分析方法（如HPLC，UPLC，LC-MS，GC，GCMS，IC，ICP-MS，HR-MS 等）为 Medicinal Chemistry ，Synthetic Chemistry 和Discovery Process Chemistry 提供客观准确和及时有效的分析数据；

利用常用结构鉴定手段（IR, HR-MS, NMR等），能够对目标产品和杂质进行结构解析和鉴定；

了解仪器的基本维修，定期进行仪器维护，排除小故障；

能够根据公司要求，及时地总结工作，完成实验研究报告；

Purify crude sample from Medicinal Chemistry, Synthetic Chemistry, and Library using various purification techniques such as Prep-HPLC.

Provide professional and rapid chiral analysis and separation services using multiple techniques such as HPLC or SFC.

Utilize various analytical methods such as HPLC, UPLC, LC-MS, GC, GC-MS, IC, ICP-MS, HR-MS, etc., to provide objective, accurate, and timely analysis data for Medicinal Chemistry, Synthetic Chemistry, and Discovery Process Chemistry.

Be capable of conducting structural analysis and identification of the target product and impurities with commonly used structural identification methods (IR, HR-MS, NMR etc.).

Understand basic instrument maintenance, perform regular instrument maintenance, and conduct trouble shooting for minor issues.

Conduct and complete experimental research reports in a timely manner according to company requirements.

任职要求

Job Requirements

分析化学、药学或相关专业博士学历，具备良好的分析化学、有机化学基础，CET-6；

熟练使用Prep-HPLC，Flash，LCMS等仪器；

熟悉常用结构鉴定手段如IR, HR-MS, NMR等；

具备良好的沟通能力和团队协作精神；

具有良好的英文基础；

遵守相应的安全规定及制度。

能适应快速的工作节奏，能够承受较强的工作压力。

Possess a Ph.D. degree in Analytical Chemistry, Pharmacy, or related field, with a strong foundation in analytical chemistry and organic chemistry, CET-6.

Familiar with commonly used structural identification methods such as IR, HR-MS, H-NMR, etc;

Demonstrate proficiency in operating instruments such as Prep-HPLC, Flash, LCMS, and other relevant equipment;

Exhibit excellent communication skills and a collaborative spirit to effectively interact with colleagues and contribute to a team environment;

Have good English skills to support effective communication and presentation of scientific information;

Adhere to relevant safety regulations and protocols in order to maintain a safe working environment;

Adapt to a fast-paced work environment and have the ability work under high pressure.